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DBCO-amine: spot the wrong reaction class

Single question

Two-step route to DBCO-amine: install the strained alkyne, then amide-couple ethylenediamine onto the pendant acid. Read the reaction class on the alkyne-forming step.

Distinguishing Suzuki coupling from base-mediated alkyne installation
Strained cyclooctyne synthesis (vic-vinyl dibromide elimination)
Reaction classes that can vs cannot form C-C triple bonds

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

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