Estrone: spot the regiochemistry flaw

Single question

A-ring aromatization step in a Torgov-style estrone endgame. Reagents and conditions match, the steroid skeleton is intact. Check which aromatic carbon ends up with the OH.

Estrone A-ring numbering (C1, C2, C3, C4)

Selective demethylation of methyl ether at C3

Why the C1-hydroxy steroid is not estrone

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

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