Longifolene: spot the stereochemistry flaw

Single question

Final Wittig methylenation in the Corey longifolene synthesis converts the penultimate ketone to longifolene. Reagents, reaction class, and conditions match. Check the ring-junction stereocenter adjacent to the new methylene.

Wittig methylenation does not invert ring stereocenters

Longifolene absolute configuration

Reading stereo on bicyclic terpene frameworks

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

Discussion

0 comments

Loading discussion...