Lactide: spot the conditions flaw

Single question

One-step formation of L,L-lactide from L-lactic acid via transesterification. The substrate is right and the product is right. Check the temperature, pressure, and water removal.

Transesterification thermodynamics

Lactide production conditions (heat + vacuum + tin catalyst)

Why aqueous conditions favor the open-chain hydroxy acid

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

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