Rhodamine B: spot the fabricated intermediate
Single questionTwo-step route to rhodamine B: phthalic anhydride plus two equivalents of 3-(diethylamino)phenol, then xanthene closure. Read the intermediate after the first condensation.
Friedel-Crafts C-acylation vs N-acylation on aminophenols
Xanthene formation mechanism
Why N-acylation kills the downstream cyclization
Find the flaw
Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.
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